Dietery SupplementIngredient – SAMe | PQQ | NMN | ET
S-adenosyl-L-methionine (SAMe)
S-adenosyl-L-methionine (SAMe) is a naturally occurring compound found in the body. It is involved in various biochemical processes including the production of neurotransmitters, DNA, and proteins.
SAMe formulated supplements are commonly used to support mental health & improved mood. It is believed to assist in the production of serotonin, dopamine & other neurotransmitters which may help with symptoms of depression, anxiety, and other mood disorders.
Additionally, SAMe has been studied for its potential benefits in supporting less pain and improvement in joint function through SAMe’s anti-inflammatory properties .
Pyrroloquinoline quinone disodium salt (PQQ)
Pyrroloquinoline quinone disodium salt (PQQ) is a powerful antioxidant that not only protects cells from oxidative damage by directly scavenging free radicals, but also plays a crucial role in regenerating other essential antioxidants such as glutathione.
Heart, nerve and liver protections; in the nervous system, it stimulates nerve growth factor (NGF) synthesis, supporting neuronal survival and synaptic plasticity; in the liver, it improves function by suppressing inflammation and fibrosis.
As an effective immune booster, PQQ significantly enhances immune function through multiple pathways. Specifically, it optimizes immune response by carefully regulating cytokine secretion (including IL-2 and IFN-γ) while simultaneously enhancing T-cell activity. Furthermore, PQQ helps reduce chronic inflammation, which is vital for maintaining proper immune homeostasis and overall wellness.
Acting as a key synthesis promoter, PQQ serves as an essential cofactor for microbial dehydrogenases in biological processes. Notably, it actively participates in redox reactions that facilitate the production of critical biomolecules like collagen and neurotransmitters. Additionally, by supporting mitochondrial function, PQQ effectively enhances the body’s overall metabolic efficiency, making it valuable for cellular energy production and maintenance.
Only Actinomycetales bacteria and certain non-yeast fungi from the Basidiomycota and Ascomycota divisions produce L-(+)-Ergothioneine (ET), a unique sulfur-containing amino acid.
As a component of the maturation medium for cumulus-oocyte complexes (COCs) to test protective function on lipid peroxide formation.
As an antioxidant compound to test type 2 diabetes patients.
As a positive control in solute carrier protein 22 A4 (SLC22A4) transport assay.